Generally, the most common capsules used in the dietary supplement industry are made from either hydroxypropyl methylcellulose (HPMC) or bovine gelatine. Both are a very flexible option that works for a wide range of formulations, applications and target markets.
HPMC is a plant-derived cellulose that has been used for vegetarian capsules since 1998. It is an ideal alternative to hard gelatine capsules owing to its low moisture content and resistance to cross-linking.

Vegetarian HPMC Capsules: Typical HPMC capsules are vegan, Halal and Kosher certified to satisfy health-conscious consumers with religious considerations. They are produced in cGMP-approved facilities and follow strict quality assurance practices to ensure the highest standard of product safety.

Enhance bioavailability:HPMC-based capsules can enhance GI tract bioavailability of poorly soluble APIs by inhibiting crystallisation of the API in the gastrointestinal tract. This can be particularly beneficial for high-energy salt form or weakly basic APIs, which are often difficult to disintegrate.

ACGcaps H+: Using a modified manufacturing process, ACGcaps(tm) H+ is a special HPMC capsule that is capable of dissolving molecules with a dissolution criterion of 0.01N HCl. Its gelling agent, carrageenan, helps to overcome the pitfalls of regular HPMC capsules that exhibit variable drug release patterns in some dissolution media.